Why Do Levels Increase?

Throughout life the level of homocysteine in plasma increases in both males and females.
The variations between sexes and populations may be explained by hormonal differences, more muscle mass in men than women and also lifestyle factors.

Lifestyle factors which increase homocysteine levels include:

  • Diet – high alcohol intake and coffee consumption reduce the absorption of vitamins
  • Smoking
  • Lack of physical exercise and excessive stress
  • Obesity
  • Drugs and certain diseases also influence homocysteine metabolism

If several of these factors are combined, their impact may be substantial